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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced Liver ... or symptoms of liver ... Drug #induced #Liver ... Idiosyncratic #differential
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Upper GI Bleed - Management ... Stabilization Concern for Liver ... GAVE (idiopathic, liver ... UGIB #GIBleed #Differential ... gastrointestinal #gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... of underlying liver ... disease, liver ... support, or liver ... Cirrhosis #Hepatology #gastroenterology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... or Cholestatic Liver ... Transaminitis #diagnosis #differential
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... MELD - Chronic liver ... US - Prior liver ... Referral #Hepatology #Gastroenterology
Liver Abscess on POCUS Ultrasound

Fever and RUQ pain/tenderness isn't always chole. In this patient population make
Liver Abscess on ... POCUS Ultrasound ... sure to sweep the liver ... with spontaneous liver ... Clinical #POCUS #Liver
The Gastroenterology Consult Primer
Guide to Calling a GI Consult
HPI:
 - Start with reason for consult
The Gastroenterology ... consult - I-liner ... Focus on prior GI/Liver ... GregoryTBrennan #Liver ... Calling #Referral #Gastroenterology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Transfer to a liver ... #AFLP #Fatty #Liver
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Regions - Frequent Differential ... amebic abscess of liver ... or elevation of liver ... Typhoid, amebic liver ... fluke, amebic liver
Liver Mass Differential Diagnosis
Solid:
 • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules
 •
Liver Mass Differential ... Cystadenoma, Polycystic liver ... Echinococcus #Liver ... #Mass #Differential