18 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
is the main clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
Systemic Therapy ... with Preserved Liver ... Hepatocellular #Carcinoma #Systemic ... #Hepatology #Gastroenterology ... #oncology #Pharmacology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Discoloration • Medications ... discoloration) • Liver ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
malaise) - Muscle pain ... Inflammation and pain ... , breast CA - Hematologic ... Treatment: - Systemic ... #dermatology #oncology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... duration), Several medications ... non-essential drug/HDS treatments ... #Algorithm #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... effusions, weight gain ... Renal Failure Treatment ... #management #hematology ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... abdomen if abdominal pain ... syndrome): - Hematologic ... ICANS: altered level ... #HemeOnc #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Red Flags: • Fever ... lesions • Severe pain ... Immunosuppressed • New medication
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Antithyroid medications ... index < 2 • EPO Level ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Metabolic syndrome • Medications ... swelling, significant pain ... nephrolithiasis, serum urate level ... • Serum urate level ... #rheumatology