10 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
and Type of Liver ... Injury #Medications ... #LiverInjury #Hepatology ... #Pharmacology # ... Causes #DILI
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... involvement, Kidney injury ... non-essential drug/HDS treatments ... for alternative causes ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... , vomiting, abdominal ... 10x ULN), ↑Tbili/Dbili ... Antithrombin Ill • Ultrasound ... #Pregnancy #hepatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... - Compartment syndrome ... Muscle swelling - Fever ... Tachycardia - N/V - Abdominal ... Diagnosis #Management #causes
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
UGT1A1 activity level ... injury ... symptoms, such as abdominal ... and stress may cause ... Congenital #bilirubin #hepatology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Kidney stones caused ... Postoperative abdominal ... distention • Abdominal ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... index < 2 • EPO Level ... aplastic anemia Treatment ... Anemia #oncology #hematology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
>20) - Obtain abdominal ... exclude other causes ... - Acute kidney injury ... HCV, DILI, HCC, ... Management #Algorithm #hepatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Normal kidney ultrasound ... Exclude other AKI causes ... Treatment Overview ... #Hepatology #Nephrology