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diagnosis management differential hematology syndrome hepatology hemophagocytic lymphohistiocytosis dermatology infectiousdiseases injury liver msk oncology arthritis blood classification fever gastroenterology hepatitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, ↓ Fibrinogen level ... • Autoimmune diseases ... Adult-onset Still disease ... Treatment: • ... #summary #rheumatology
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
Causes of Acute ... Diagnosis Algorithm ... • Sickle Cell disease ... #Fever #Acute ... #causes
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... can mimic common infections ... presents as an acute ... : • Infection ... #hematology
Pediatric Vomiting - Gastrointestinal and Systemic Causes - Differential Diagnosis Algorithm Hepatobiliary: • Acute Hepatitis • Acute
Pediatric Vomiting ... Gastrointestinal and Systemic Causes ... Differential Diagnosis Algorithm ... #Causes #Peds # ... Pediatrics
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... hypersensitivity syndromes • HLH ... Treatment: • Corticosteroids ... #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Differential #Diagnosis #Algorithm
Pediatric Acute Abdominal Pain - Differential Diagnosis Algorithm Generalized/Migratory: • Intussusception • Gastroenteritis • Viral Illness •
Pediatric Acute ... Differential Diagnosis Algorithm ... Urinary Tract Infection ... #Causes #Peds # ... Pediatrics
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelofibrosis Infectious ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Renal Disease, Liver ... Inflammation, Chronic Infection ... #Causes #Hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Parenchyma • Infectious ... Hepatitis, TPN • Infectious ... Differential #Diagnosis #Causes ... #Acute #algorithm
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