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Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... thrombocytopenia • Liver ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Hepatomegaly - Liver ... subset counts ↓ • Liver ... Viral hepatitis Diagnosis ... antibody test) Treatment ... #HIV #diagnosis
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
stores in the liver ... beta-oxidation in the liver ... elevates the stress level ... for Refeeding Syndrome ... #diagnosis #differential
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... GH stimulates liver ... Beckwith Wiedemann syndrome ... • Serum IGF-1 level ... Endocrinology #Treatment
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... • Hepatorenal Syndrom ... (HRS) • Liver ... SBP) #ESLD #Liver ... Complications #diagnosis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... pathology (low level ... Transaminitis #diagnosis
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... progressing to acute liver ... Liver transplant ... #differential #diagnosis
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
manifestations of acute liver ... Hepatorenal syndrome ... abnormalities Liver ... manifestations #acute #liver ... Signs #Symptoms #Diagnosis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... Hemolysis, Elevated Liver ... exchange 3) Fatty liver ... coagulation defects and liver ... obstetrics #hematology #diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... disease, liver ... support, or liver ... gastroenterology #management #diagnosis