17 results
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... #Pediatrics #Peds ... #Febrile #Infant ... Stratification #Fever
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... Imaging: CXR- pulmonary ... initiation • Differential ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
acute or subacute febrile ... following: • Fever ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... TLS #diagnosis #management ... #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
: • 80% have fever ... decubitus - air fluid level ... Intervention: - Fevers ... Lung #Abscess #pulmonary ... #differential #
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology ... #diagnosis #management
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... Diagnosis #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
decrease in HIV-1 RNA level ... - Pneumonitis (fever ... Fever, chills, lack ... Leishmaniasis Differential ... #Diagnosis #Management