103 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... cholestasis: • Fever ... Liver transplant ... hepatology #hepatitis #differential
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... the first-line treatments ... #Pharmacology #Pathophysiology
Rodent-associated Bacterial infections: Leptospirosis, Rat-bite fever, Tularemia, Plague 

#rodent
#infections
#leptospirosis
#tularemia
#ratbitefever
#plague
#rats
#infectiousdisease
#fever
#differential
#diagnosis
#management
#treatment
#table
Leptospirosis, Rat-bite fever ... infectiousdisease #fever ... #differential ... #management #treatment
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
DILI and Type of Liver ... #Medications #Differential ... LiverInjury #Hepatology #Pharmacology
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Treatment of Wilson's ... Aims to reduce level ... Wilsons #Disease #Treatment ... #management #pharmacology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... range of potential pathophysiologic ... - Pathophysiology ... instability - New-onset fever ... Targetoid #Algorithm #Differential
Migraine - Preventative Treatments

 • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin
 • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
- Preventative Treatments ... Cyproheptadine * Level ... #Preventative #Treatment ... prophylaxis #prevention #pharmacology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver ... infiltration) Differential ... diagnosis #management #pathophysiology
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... mortality at a higher level ... Ranges #Toxicology #Pharmacology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
of O2 at tissue level ... of O2 at tissue level ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential