166 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Acute sickle cell hepatic ... Supportive with treatment ... crisis Acute Hepatic ... #SickleCell #Disease
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... : Fever, Arthralgia ... splenomegaly • Hepatic ... diagnosis #management #treatment ... #rheumatology
"Playboy Bunny" sign, seen w/hepatic congestion due to R heart failure.

Dr. Josie Acuna @jgacuna

#Hepatic #Congestion #Bunny
" sign, seen w/hepatic ... Acuna @jgacuna #Hepatic ... Sign #Playboy #Clinical ... #Liver #Ultrasound
Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Clinical Examination ... for Liver and Biliary ... Diseases 1) Hands ... Flapping tremor (hepatic ... Palpable gallbladder, Hepatic
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Treatment of Wilson's ... Disease • D-penicillamine ... Aims to reduce level ... #Treatment #management ... #pharmacology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... • Infiltrative diseases ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Veno-occlusive disease
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g. celiac disease ... Medications - Heparin ... ) • Advanced Liver ... Disease - Alcohol ... comparison #diagnosis #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... weeks • Typical clinical ... post-partum • Typical clinical ... post-partum • Typical clinical ... #Disease #Pregnancy
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... ultrasound: A concerning ... of air in the hepatic ... #hepatology #liver ... #pocus #clinical
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++ (Plt, Hb), Hepatic ... , ↓ Fibrinogen level ... #summary #rheumatology