81 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... only curative treatment ... Myelodysplastic #Syndrome ... Diagnosis #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... #oncology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Rheumatoid Nodules, Pulmonary ... Instability, Felty's Syndrome ... RA #diagnosis #rheumatology ... #signs #symptoms
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
• Indolent symptoms ... to rnonths • Fever ... , hemoptysis Treatment ... Abscess #Diagnosis #Pulmonary
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... less systemic symptoms ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... - 80% have fever ... organ damage • Treatment ... diagnosis #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
index < 2 • EPO Level ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment ... indicate preferred treatment ... the perceived level ... of symptoms and ... #Management #Pulmonary
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... - Thalassemia, Liver ... PD deficiency, Pulmonary ... Hemolytic uremic syndrome ... #differential #hematology