22 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... hepatomegaly and anemia ... progressing to acute liver ... Liver transplant ... #diagnosis
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypothyroid • Liver ... #Macrocytic #Anemia ... #differential # ... diagnosis #algorithm ... #hematology #workup
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... BrighamChiefs #Liver ... #differential # ... diagnosis #icp #
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... Hemolysis, Elevated Liver ... exchange 3) Fatty liver ... #diagnosis #table ... #comparison
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... elevation DDX of Hepatic ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Hepatocellular Level ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... coagulation defects and liver ... #Diagnosis #Comparison ... #Table
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... #hepatology
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... , Metastasis #Liver ... CT #radiology #differential ... #diagnosis #comparison ... #table #appearance
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... , Metastasis #Liver ... POCUS #radiology #differential ... #diagnosis #comparison ... #table #appearance