35 results
diagnosis hepatology oncology anemia aplastic blood cardiology dermatology differential disease hemophagocytic hlh lymphohistiocytosis product reactions aclf activation aki amiodarone apml
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Brain Failure Lung ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
megaloblastic anemia Treatment ... if neutropenic fever ... progress to MDS or acute ... Anemia #diagnosis #management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... - ACS, AKI, acute ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
Susac Syndrome - ... Evolution Acute ... arterioles - Treatment ... Triad #Diagnosis #Management ... #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : • Common: fever ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Orthopedic Emergencies Compartment Syndrome • An increase in compartment pressure to the point where tissue perfusion is
• Initial Management ... Ensure leg is at level ... days after an acute ... including DM • Treatment ... #treatment
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
biliary, renal, lung ... with response to treatment ... hypergammaglobulinemia, ↑ acute ... Disease #diagnosis #management ... #rheumatology
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