28 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... AIHA, Transfusion reactions ... Laboratory Tests ... #Diagnosis #hematology
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint Pain ... - Differential ... Diagnosis Algorithm ... Inflammatory #JointPain #MSK ... #Differential #
Vertebral Body Abnormalities

A sheet of common (and uncommon) vertebral body findings, because a completely “normal” spine
Sickle Cell Neurofibromatosis ... Abnormalities #Radiology ... #MSK #Pathology ... Anomalies #Spine #Diagnosis ... #differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Other: Transfusion reaction ... - Transfusion reaction ... Extravascular #Causes #differential ... #diagnosis #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... infection • Lyme disease ... blennorrhagicum • Reactive ... #skin #rashes #differential ... #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell ... Disease Vaso-occlusive ... #differential # ... diagnosis #causes ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... Fever/Chills/Joint pain ... Effusions #causes #differential ... #diagnosis #msk
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
- Differential ... Diagnosis Algorithm ... Occlusion • Sickle ... Peripheral Vascular Disease ... Vascular #JointPain #MSK
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
) Differential Diagnosis ... aphthae : SLE, Reactive ... Arthritis: SLE, Reactive ... Nonsurgical abdominal pain ... signs #symptoms #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... categories of joint disease ... #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis