12 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Hyporeflexia: • Hypercalcemia ... Deep coma (any cause ... differential #diagnosis #table ... #neurology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... aspiration #Potassium #Binding ... #pharmacology #table ... #comparison #binders
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
From organ/cavity lining ... ) Poorly localized ... Pain #Mechanisms #Neurology ... Differential #Diagnosis #Algorithm ... #Causes
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
patients with CKD ... require phosphate binding ... since they are not able ... restricted due to hypercalcemia ... Purposes Only* #CKD
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... Differential Diagnosis Algorithm ... Hyperoxaluria • Hypercalcemia ... Hyperphosphatemia #CKD ... #Causes
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Differential Diagnosis Algorithm ... syndrome • AKI/CKD ... Hyperthyroidism • Hypercalcemia ... HTN #Secondary #Nephrology ... Differential #Diagnosis #Algorithm
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
with previously stable ... heart failure, neurologic ... disorders including hypokalemia ... parenchymal disease: CKD ... Neurologic disorders
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
VBG (acidosis), CK ... only if no clear cause ... Elimination (see Table ... Treatments: • K-Binding ... Treatment #potassium #nephrology
Rapid, increasing signs of extrapyramidal symptoms (EPS) is an important key feature of NMS. EPS, associated
about 95% of NMS cases ... creatine kinase (CK ... Laboratory findings ... NeurolepticMalignant #Comparison ... #Table