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rheumatology management differential dermatology oncology erythematosus sle systemic vasculitis signs symptoms causes comparison cutaneous monoclonal gammopathy hepatology photo algorithm alopecia
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis ... vasculitis Clinical ... manifestations - Skin ... neuropathy Treatment ... with refractory disease
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
deposits: Type I cryoglobulinemia ... activity: Type II cryoglobulinemia ... Cold agglutinin disease ... manifestations #dermatology ... #skin #clinical
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Syndrome: • Clinical ... • Autoimmune diseases ... Labs/Diagnosis: ... (e.g. systemic lupus
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... Chain deposition disease ... antiphospholipid syndrome ... S - Systemic Lupus ... #differential #hematology
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Interstitial lung disease ... viruses. systemic lupus ... and Sjogren's syndrome ... in absence of skin ... #differential #diagnosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection • Lyme disease ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... • Typically located ... purpura • Mixed cryoglobulinemia ... • Goodpasture syndrome ... #rash #diagnosis
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... SLE : systemic lupus ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential Diagnosis ... Urticarial/LCV) - Cryoglobulinemic ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #differential #diagnosis
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