49 results
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop ... Diuretic Action ... Panel A, loop diuretics ... compete with chloride ... binding to sodium–potassiumchloride
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... or thiazide diuretics ... - Normal/low ... pressure: Active diuretic
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... #causes #potassium
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... Remote use of loop ... or thiazide diuretics ... alkalosis • Normal/low ... of sodium and potassium
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... Fluids Shift potassium ... renal function) - Loop ... diuretic (often ... LouLectures #Hyperkalemia
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... vomiting) • Low ... • Discontinued diuretic ... #potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... with hypokalemia ... High Urine Cl - Loop ... diuretics, Mg2+ ... #urine #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... Clinicians should also look ... Post-hypercapnia • Diuretics ... differential #diagnosis #algorithm ... causes #nephrology #potassium
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Ureterosigmoidostomy, jejunal loop ... , ileal loop ... Potassium-sparing ... diuretics (amiloride ... loads (ammonium chloride
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... Piretanide Potassium ... Pharmacology #nephrology #conversion ... #loop #thiazide