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Hyperkalemia Hypokalemia - Differential Diagnosis and Management Algorithm

Dr Pravin Patel

#Hypokalemia #Hyperkalemia #potassium #differential #diagnosis #management
Hyperkalemia Hypokalemia ... - Differential ... and Management Algorithm ... Pravin Patel #Hypokalemia ... #Hyperkalemia #
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
Treatment of hyperkalemia ... determine response to diuretic ... #hyperkalemia ... #diuresis #nephrology ... #algorithm
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Thyrotoxicosis Medications ... • Discontinued diuretic ... MatthewHoMD #Hypokalemia
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... anhydrase inhibitors, loop ... syndrome (mimics loop ... or induced) #Hypokalemia ... #Causes #differential
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... Diagnosis Algorithm ... Renal loss • Medication ... Hypomagnesemia • Osmotic diuresis ... amzn.to/2LmUODZ #Hypokalemia
Ethacrynic acid - Conversion
Only loop diuretic without a sulfonamide substituent.
Rarely used alternative in patients who have
Ethacrynic acid - Conversion ... Only loop diuretic ... Ethacrynic #acid #Conversion ... #pharmacology #indications ... #diuretics #loop
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause of hypokalemia ... Clinicians should also look ... Hypomagnesemia-induced hypokalemia ... Cushing's syndrome #hypokalemia
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... - Loop and ... abnormalities - Hypercalcemia ... - Hypokalemia ... Hypomagnesemia #Differential
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... antagonists (MRA) - Hyperkalemia ... higher risk of hyperkalemia ... Angioneurotic edema, Hyperkalemia ... - Pregnancy, Hyperkalemia
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... Furosemide and other loop ... panitumumab) #Drugs #hypokalemia ... #differential #