113 results
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
(B) Treatment algorithm ... Total loop diuretic ... intravenous; SGLT2‐I, sodium–glucose ... following a single loop ... #CHF #Algorithm
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... as no effect on sodium ... Pharmacology #nephrology #conversion ... #loop #thiazide ... #classes
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... syndrome (mimics loop ... #Hypokalemia #Causes ... #differential #
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... • Osmotic diuresis ... #Diagnosis #Causes ... #nephrology #sodium
Hyponatremia Treatment Algorithm

CHF, Cirrhosis - Fluid restriction
SIADH - Fluid restriction
 - Consider salt tablets if etiology
Algorithm CHF ... consider adding loop ... diuretic Reset ... -> free water diuresis ... #Algorithm #Management
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity Treatment ... Amyl nitrite - causes ... binds cyanide - Sodium ... thiosulfate enhances conversion ... Pathophysiology #Management #Treatment
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Metabolic Alkalosis - Differential ... Diagnosis Algorithm ... Remote use of loop ... or thiazide diuretics ... #causes #urinary
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential ... Diagnosis Algorithm ... Clinicians should also look ... Post-hypercapnia • Diuretics ... #diagnosis #algorithm
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... - Differential ... Diagnosis Algorithm ... Urine Mg > 10g • Loop ... #Differential #
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... pressure: Active diuretic ... the indicated causes ... #nephrology #differential