121 results
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
fludrocortisone step 3 = diuretic ... determine response to diuretic ... criticalcare #treatment #diuretics ... #diuresis #nephrology ... #algorithm
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... . mannitol) 3) Loop ... diuretic (e.g. ... Thiazides-type diuretics ... #pharmacology #nephrology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Pathophysiology - Diuretic ... Sites of Action Diuretics ... urearetics) 3) Loop ... Pathophysiology #Diuretics ... Sites #Action #nephrology
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypodipsia - Renal ... hypernatremia - Osmotic diuretic ... , Loop diuretics ... Postobstructive diuresis ... Comparison #Table #Nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Villous adenoma Renal ... anhydrase inhibitors, loop ... chewing tobacco, Renal ... syndrome (mimics loop ... differential #diagnosis #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... DIURETICS • Furosemide ... Tolvaptan #Diuretics ... summary #table #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop ... #Pharmacology #nephrology ... #conversion #loop
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Spironolactone Loop ... Diuretics Thiazides ... Acetazolamide #Diuretics ... pathophysiology #nephrology
Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Diuretics #Diuretics ... #Pharmacology #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... loss (Diarrhea) Renal ... • HTN Absent: Loop ... and thiazide diuretics ... potassium #low #nephrology