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diagnosis differential causes hypokalemia management potassium treatment diuretics metabolic alkalosis hypercalcemia hypomagnesemia hyponatremia pharmacology workup magnesium renal sodium table chloride
Treatment of hyperkalemia via kaliuresis step 1 = volume resuscitation if hypovolemic step 2 = consider fludrocortisone step
Treatment of hyperkalemia ... determine response to diuretic ... #hyperkalemia ... #diuresis #nephrology ... #algorithm
Nephron Pathophysiology - Diuretic Sites of Action Diuretics 1) Acetazolamide/canagliflozin 2) Osmotic agents (mannitol, urearetics) 3) Loop agents (eg, furosemide) 4)
Nephron Pathophysiology ... - Diuretic Sites ... urearetics) 3) Loop ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... #nephrology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... anhydrase inhibitors, loop ... syndrome (mimics loop ... or induced) #Hypokalemia ... differential #diagnosis #nephrology
Mechanism of Action of Diuretics Amiloride, Triamterene, Spironolactone Loop Diuretics Thiazides Acetazolamide #Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Spironolactone Loop ... Diuretics Thiazides ... #pharmacology #pathophysiology ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... vomiting) • Low ... • Discontinued diuretic ... #nephrology #low
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Medications - Loop ... and thiazide diuretics ... abnormalities - Hypercalcemia ... - Hypokalemia ... Differential #Diagnosis #Low
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... Clinicians should also look ... Post-hypercapnia • Diuretics ... differential #diagnosis #algorithm ... #causes #nephrology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop ... #Pharmacology #nephrology ... #conversion #loop
Hormones Acting on the Nephron - Diuretics and Their Site of Action 1) Acetazolamide 2) Osmotic
the Nephron - Diuretics ... mannitol) 3) Loop ... Diuretics (e.g. ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
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