19 results
Ethacrynic acid - Conversion
Only loop diuretic without a sulfonamide substituent.
Rarely used alternative in patients who have
Only loop diuretic ... hypersensitivity reaction ... diuretic. ... #pharmacology #indications ... #diuretics #loop
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
Flowchart to diuretic ... (B) Treatment algorithm ... Total loop diuretic ... #Diuretic #Diuresis ... HeartFailure #Cardiology #Management
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... diuretics, and ... thiazide-like diuretics ... diuretic use),
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of diuretics ... diuretics, Thiazide‐like ... diuretics, MRA, ... Absorption #Diuretics ... #Thiazide #CHF
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... CONCENTRATION MEDICATIONS ... • Start with LOOP ... are short acting ... aldosterone states (CHF
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Can Be On" • Diuretics ... Reducing: • Diuretics ... diuretics preferred ... metolazone in diuretic ... #medications #chf
Hyponatremia Treatment Algorithm

CHF, Cirrhosis - Fluid restriction
SIADH - Fluid restriction
 - Consider salt tablets if etiology
Algorithm CHF ... consider adding loop ... diuretic Reset ... -> free water diuresis ... #Algorithm #Management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... irrigation • Management ... +2Cl- Symport (Loop ... Tolvaptan) • Treatment ... #Pharmacology #Medications
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... improve GFR - Diuresis ... hypertonic Amp IVP • Diuretics ... (IV loop diuretic ... diuretic (lasix
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... anemia) • G-CSF ... Thyrotoxicosis Medications ... GI losses (NG suction ... • Discontinued diuretic