24 results
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... diuretics, and ... , Osmotic diuresis ... (mimics loop diuretic
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Remote use of loop ... or thiazide diuretics ... diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... anemia) • G-CSF ... • Refeeding syndrome ... GI losses (NG suction ... • Discontinued diuretic
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... • Start with LOOP ... DIURETICS which ... are short acting ... aldosterone states (CHF
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... • Metabolic alkalosis ... +2Cl- Symport (Loop ... Diuretics) (Bumetanide ... Tolvaptan) • Treatment
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Remote use of loop ... or thiazide diuretics ... diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
vomiting/ nasogastric suction ... • Thiazide or loop ... diuretics after ... renal tubule diuretic ... diuretics actively
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... improve GFR - Diuresis ... hypertonic Amp IVP • Diuretics ... (IV loop diuretic ... diuretic (lasix
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... Non-reabsorbable anion ... High Urine Cl - Loop ... diuretics, Thiazide ... diuretics, Mg2+
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... Hypochloremic metabolic alkalosis ... Surreptitious diuretic ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology