11 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... of Action Diuretics ... #Diuretics #Sites ... #Action #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Diuretics and Their ... mannitol) 3) Loop ... Diuretics (e.g. ... #Nephrology #Nephron ... #Diuretics #Hormones
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... diuretics, and ... , Osmotic diuresis ... (mimics loop diuretic
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... • Start with LOOP ... are short acting ... aldosterone states (CHF ... Early nephrologv
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... • Metabolic alkalosis ... +2Cl- Symport (Loop ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Remote use of loop ... or thiazide diuretics ... blood pressure: Active ... diuretic use, Bartter ... urine #Algorithm #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
vomiting/ nasogastric suction ... diuretics after ... renal tubule diuretic ... diuretics actively ... Diagnosis #Causes #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... anemia) • G-CSF ... • Refeeding syndrome ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic Alkalosis ... tubular transport • Diuretics ... (loop/thiazide) ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
G-K), K-sparing diuretics ... improve GFR - Diuresis ... hypertonic Amp IVP • Diuretics ... (IV loop diuretic ... diuretic (lasix