14 results
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... or induced) #Hypokalemia ... #Causes #differential ... #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... • Discontinued diuretic ... MatthewHoMD #Hypokalemia ... Diagnosis #Algorithm
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Hypokalemia ... Hyperkalemia ... Drug-induced hyperkalemia ... Potassium-sparing diuretics ... #diagnosis #causes
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Remote use of loop ... or thiazide diuretics ... diuretic use, Bartter ... #nephrology #differential ... #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... Family history of hypokalemia ... • Unexplained hypokalemia ... Surreptitious diuretic ... #Hypokalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... Diagnosis Algorithm ... diuretics / Bartter's ... #Nephrology #Differential ... #Diagnosis #Algorithm
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... G-K), K-sparing diuretics ... improve GFR - Diuresis ... (IV loop diuretic ... diuretic (lasix
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Alkalosis - Differential ... Diagnosis Algorithm ... tubular transport • Diuretics ... #Nephrology #Differential ... #Diagnosis #Algorithm
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... +2Cl- Symport (Loop ... Kidney stones caused ... Tolvaptan) • Treatment ... #Medications #Table
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... • K sparing diuretics ... diagnosis #causes