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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... polystyrene sulfonate • Patiromer ... Hyperkalemia #treatment #pharmacology ... #table #comparison ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ; hypokalemia Patiromer ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... : SIADH, Renal Sodium ... can be high or low ... differential #diagnosis #table ... #sodium #nephrology
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Low pill burden. ... edgarvlermamd - Nephrology ... Phosphate #Binders #Table ... #Comparison #Pharmacology ... #Nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
increased risk of low ... edgarvlermamd - Nephrology ... Phosphate #Binders #Table ... #Comparison #Pharmacology ... #Nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... alkalosis • Normal/low ... the excretion of sodium ... and potassium acid ... #nephrology #differential
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Elimination (see Table ... acidosis) • Low ... effectiveness - Patiromer ... Management #Treatment #potassium ... #nephrology #K