14 results
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Low pill burden. ... Velphoro, ferric citrate ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... • SPS - Sodium ... #Hyperkalemia # ... #pharmacology #table ... #comparison #nephrology
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... Chelators, Lactate, Citrate ... #Workup #Differential ... Diagnosis #Algorithm #nephrology ... #calcium
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Inexpensive - Treats hypocalcemia ... burden Ferric citrate ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pump - Digoxin works ... - Hyperkalemia ( ... Because digoxin binds ... , in states of hypokalemia ... (or low potassium
Management of Pediatric Kidney Stones
Acute Managment:
 • Pain relief: NSAIDs, opioids
 • Facilitating passage of stone:
HYPERCALCIURIA - Calcium ... protein - Low ... sodium diet ... citrate, neutral ... Management #Pediatrics #nephrology
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
: - IV calcium ... in 4 mL) - IV sodium ... - Consider K+ binders ... reinitiate and titrate ... Chronic #treatment #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... 4 mEq/L • Calcium ... same line - Citrate ... Is Dangerous in Hyperkalemia ... decreased renal blood flow
Citrate Anticoagulation Toxicity

Hypernatremia (HyperNa):
 - Citrate solutions may have ↑ sodium content and should be paired
solutions may have ↑ sodium ... binds Mg: this ... circulation → ↓Mg Hypocalcemia ... dysfunction or low ... Toxicity #toxicology #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... (renal potassium ... Hypocalciuria (spot urine, calcium-creatinine ... Syndrome #diagnosis #nephrology