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diagnosis comparison phosphate differential management anticoagulation citrate diuresis diuretics excretion framework gitelman hyperkalemia hypokalemia hyponatremia hypophosphatemia hypotonic medications pathophysiology physiologic
Phosphate Binders - Pros and Cons Calcium carbonate (TumsTM) - Most inexpensive, antacid properties useful for
Low pill burden. ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology # ... Nephrology
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Hyperkalemia • SPS - Sodium ... Hyperkalemia #treatment #pharmacology ... #table #comparison ... #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Antacids, Phosphorus binders ... Glucose, Acute resp. alkalosis ... FEPO4 ≥ 5% - Renal ... • Normal or Low ... Workup #phosphate #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... Primary polydipsia), Low ... differential #diagnosis #table ... #sodium #nephrology
Characteristics of Commonly Used Phosphate Binders Aluminum - Potent and effective - Useful for
Used Phosphate Binders ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology # ... Nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... • Metabolic alkalosis ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Normal or low ... • Hypokalemia (renal ... Syndrome #diagnosis #nephrology
Citrate Anticoagulation Toxicity Hypernatremia (HyperNa): - Citrate solutions may have ↑ sodium content and should be paired
solutions may have ↑ sodium ... HypoMg): - Citrate binds ... dysfunction or low ... metabolism Metabolic alkalosis ... Toxicity #toxicology #nephrology
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