11 results
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Velphoro, ferric citrate ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology # ... Nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Hyperkalemia • SPS - Sodium ... Hyperkalemia #treatment #pharmacology ... #table #comparison ... #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
burden Ferric citrate ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology # ... Nephrology
Citrate Anticoagulation Toxicity

Hypernatremia (HyperNa):
 - Citrate solutions may have ↑ sodium content and should be paired
solutions may have ↑ sodium ... binds Mg: this ... dysfunction or low ... metabolism Metabolic alkalosis ... Toxicity #toxicology #nephrology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Lactated Ringers ... same line - Citrate ... filtration - Renal ... blood flow and ... NS #comparison #pharmacology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Antacids, Phosphorus binders ... Glucose, Acute resp. alkalosis ... FEPO4 ≥ 5% - Renal ... • Normal or Low ... Workup #phosphate #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... Primary polydipsia), Low ... differential #diagnosis #table ... #sodium #nephrology
Management of Pediatric Kidney Stones
Acute Managment:
 • Pain relief: NSAIDs, opioids
 • Facilitating passage of stone:
protein - Low ... sodium diet ... - Potassium Citrate ... Monitoring for extra-renal ... Management #Pediatrics #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... • Metabolic alkalosis ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Normal or low ... • Hypokalemia (renal ... Syndrome #diagnosis #nephrology