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differential management algorithm diuresis diuretics epithelial excretion framework gitelman hyperkalemia hypernatremia hypokalemia hyponatremia hypophosphatemia hypotonic inherited k kidney medications pathophysiology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... mOsm/kg - Implies renal ... • Euvolemic (Low ... #nephrology #sodium
Workup for Hypophosphatemia - Differential Diagnosis Framework Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... - Differential Diagnosis ... Glucose, Acute resp. alkalosis ... FEPO4 ≥ 5% - Renal ... #phosphate #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... Epithelial Cells Renal ... #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... #differential #diagnosis ... #table #sodium ... #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Metabolic alkalosis ... disequilibrium syndrome • Diagnosis ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Normal or low ... Gitelman #Syndrome #diagnosis ... #nephrology #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... reabsorption) Workup ... Elimination (see Table ... acidosis) • Low ... Treatment #potassium #nephrology
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