55 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... permeability Diagnosis ... Puncture, EEG Treatment ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... 60-80% - Low ... life-threatening • Treatment ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... in >90% - Low ... sle #comparison #table ... #rheumatology #diagnosis ... #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... 1.5 High CO / Low ... Abdominal compartment syndrome ... #criticalcare # ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Pulm: Hypoxia, dyspnea ... , Elevated Cr, Low ... calcium • Treatment ... #TLS #diagnosis ... #management #hematology
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
essential to determine treatment ... CCB, BB, BRASH syndrome ... cytokine release syndrome ... Undifferentiated #Shock #diagnosis ... guyton #curves #criticalcare
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management
Post-Intensive Care Syndrome (PICS)
Symptoms of PICS:
 - Physical Domain: Generalized weakness, Fatigue, Difficulty walking
 - Cognitive
Post-Intensive Care Syndrome ... disturbance/loss, Slow ... guide targeted treatments ... #PICS #diagnosis ... #management #criticalcare
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... renal failure Clinical ... Pulmonary: dyspnea ... skin (16-32%): lupus ... #Management #Signs
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... antibodies (aPL): • Lupus ... at least: • 1 clinical ... to be present Treatment ... #management #anticoagulation