15 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
MAHA: TTP, HUS, DIC ... AIHA, Cold AIHA, Transfusion ... Defects, Drugs, Liver ... - Peripheral Blood ... #Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Liver diseases ... coagulopathy (DIC ... #differential # ... hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Normal Blood Smear ... #Causes #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... eruptions, diarrhea, liver ... Malaria, Borrellia (Lyme ... #diagnosis #management ... #hematology #reactions
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... MAHA: TTP, HUS, DIC ... #Diagnosis #causes ... classification #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation (DIC ... • Intrinsic RBC ... #differential # ... diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Severe Liver ... hydration • RBC ... #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... pain, dark urine, DIC ... Malaria, Borrellia (Lyme ... #diagnosis #management ... #hematology #reactions
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... disease), HBsAg ... #Diagnosis #Causes ... #Workup #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... rapidly develops (DIC ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... #Pregnancy #hepatology