24 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Differential Diagnosis ... vasculitis (inflamed blood ... #rash #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... Cryofibrinogenemia Clinical ... : • + Clinical ... cryoglobulins • Negative causes ... #rheumatology #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Myeloproliferative disease ... Testosterone - Coumadin skin ... Venous #Arterial #pathophysiology ... #hematology #differential
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... of high parity blood ... without other cause ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... resembling rashes caused ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... infections with skin ... Malaria, Borrellia (Lyme ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... infections with skin ... Malaria, Borrellia (Lyme ... #Transfusions #diagnosis ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... deficiency • blood ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... onset [33-74%] • Blood ... severity of the disease ... #rheumatology #dermatology ... #diagnosis