67 results
Demyelinating Diseases - Differential Diagnosis
 • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE
 •
Demyelinating Diseases ... : MS, ADEM, NMO, ... Polyarteritis nodosa, SLE ... Infectious: HIV, Lyme ... Demyelinating #Diseases
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
disease • Rosacea ... disease Erythema ... Sarcoidosis • Crohn's disease ... #skin #rashes #differential ... #diagnosis #rheumatology
Lyme Disease: Clinical diagnosis. Likely if recent hiking, travel to endemic area, erythema migrans (EM), an
Lyme Disease: Clinical ... diagnosis. ... Treatment is doxycycline ... for disease involving ... #Symptoms #Early
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... context of other symptoms ... likely it will be clinically ... ANA #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... • Whipple's disease ... , Lyme disease, ... #joint #pain #differential ... #diagnosis #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... cancers • Systemic diseases ... autoinflammatory diseases ... AdultOnset #Stills #Disease ... #treatment #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
constitutional symptoms ... Disease OLIGOARTHRITIS ... whippleii (Whipple's disease ... disease) • Mycobacterium ... #Diagnosis #MSK
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
and less common diseases ... and treatment can ... Vogt-Koyanagi-Harada (VKH) disease ... polychondritis • Behcet disease ... #inflammatory #differential
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Inflammatory Bowel Disease ... Arthropathy with Crohn’s Disease ... systemic autoimmune disease ... Erythematosus (SLE ... Joint #Disorders #msk
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
auto-immune, Infectious diseases ... sclerosis, Still's disease ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #rheumatology