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Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... morphologically mature B Lymphocytes ... rnature-appearing lymphocytes ... 500/uL clonal B lymphocytes ... immunophenotype Clinical
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... salivary ducts Clinical ... UIP, NSIP): • Lymphocytic ... phenomenon (16%) MSK
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Pathogenesis and Clinical ... Findings B & T lymphocyte ... hyperplasia Note: B & T lymphocytes
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Chronic Lymphocytic ... Leukemia (CBC with Lymphocytes ... - Monoclonal Lymphocytes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cell neoplasm • Lymphocytes ... Orange or Hep C Clinical ... Absolute blood lymphocyte
Tuberculous Pleural Effusions - Tests and Biomarkers Age + fever + red blood cells + ADA -
leukocyte count + lymphocytes ... specificity ADA + lymphocyte
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
prognosis • Nodular Lymphocyte ... cells absent, lymphocyte ... Mixed Cellularity, Lymphocyte ... Rich, Lymphocyte ... Amy Chung, MD, MSc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... CLL (Chronic Lymphocytic ... Leukemia): • Lymphocytes ... Nodes: • Small lymphocytic ... ) and/or Small Lymphocytic
White Blood Cell Maturation Chart #Pathology #WBC #Maturation #Lineage #Chart #Leukocyte #Myeloid #Myeloblast #Lymphocyte
Myeloid #Myeloblast #Lymphocyte
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 Peripheral Blood shows a subset of atypical lymphocytes with hairy-like cytoplasmic projection. #Clinical #Path #BloodSmear #Blood #Smear
subset of atypical lymphocytes ... #Clinical #Path
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