13 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... • Systemic Lupus ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Age > 50 • Chronic
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... • (Peripheral eosinophilia ... bruising, bleeding, infection ... plaques) AML Dx
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
parvovirus B19 infection ... parvovirus B19 infection ... • Rheumatic fever ... Amyloidosis • Eosinophilic ... lesions • Discoid lupus
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Infections 2. ... symptoms - Headache, fever ... infiltration (lymphocytes ... neutrophils and eosinophils ... Urticaria #diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... 9) Unexplained fever ... , when infection ... including in children (pediatric ... erythematosus #rheumatology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Framework The DDx ... 2nd pass = Chronic ... ESRD & CAD • Eosinophilic ... • Parasitic infections ... #Diagnosis #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
about bacterial infections ... acute rheumatic fever ... about indolent infections ... with bacterial infection ... prosthetic joint infection
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM) Infections ... Factors For NTM Infections ... status NTM Cause ... • Disseminated infections ... lung infections
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• EGPA: - Eosinophilia ... , asthma, chronic ... tract, and often causes ... to exclude are infections ... #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Skin Disease Classification ... permanent alopecia Differential ... fibromyalgia) • Infections ... : • Chronic B-cell