14 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Disorders: • Chronic ... Diabetes/DKA Infections ... : • helminth infections ... #hematology #basophils
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Age > 50 • Chronic ... Lymphocytic Leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Malaise, bleeding, infections ... pain, bleeding, infections ... , basophilia, and ... bruising, bleeding, infection
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphadenopathy • Fevers ... weeks without infection ... Scoring system: DDX ... #Lymphocytic #Leukemia
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
(neutrophils, eosinophils ... monocytes, & lymphocytes ... ., C difficile infection ... , rickettsia infections ... and bacterial infections
Causes of Night Sweats - Differential Diagnosis
 • Malignancy: Lymphoma, Leukemia, Other neoplasm
 • Infections: Human
Malignancy: Lymphoma, Leukemia ... Other neoplasm • Infections ... avium complex, Infectious ... mononucleosis, Fungal infections ... Endocarditis, Other infection
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Weight loss - DDX ... : - Infection ... to the knee Infectious ... Disease Post-Infectious ... Hematologic - Leukemia
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Infections 2. ... symptoms - Headache, fever ... infiltration (lymphocytes ... neutrophils and eosinophils ... Urticaria #diagnosis #rheumatology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Framework The DDx ... 2nd pass = Chronic ... ESRD & CAD • Eosinophilic ... • Parasitic infections ... #Diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... and thymoma DDX ... virus (EBV) • Leukemia