17 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Age > 50 • Chronic ... Lymphocytic Leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Malaise, bleeding, infections ... pain, bleeding, infections ... • (Peripheral eosinophilia ... bruising, bleeding, infection
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphadenopathy • Fevers ... weeks without infection ... Scoring system: DDX ... #Lymphocytic #Leukemia
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... ) B symptoms → fevers ... Complications: 1) Infection ... #Lymphocytic #Leukemia ... hemeonc #diagnosis #management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Secondary Causes ... hypersensitivity - Infection ... Myeloproliferative HES - Lymphocytic ... #differential # ... management #eosinophils
Causes of Night Sweats - Differential Diagnosis
 • Malignancy: Lymphoma, Leukemia, Other neoplasm
 • Infections: Human
Malignancy: Lymphoma, Leukemia ... Other neoplasm • Infections ... avium complex, Infectious ... mononucleosis, Fungal infections ... Endocarditis, Other infection
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
(neutrophils, eosinophils ... , monocytes, & lymphocytes ... ., C difficile infection ... , rickettsia infections ... and bacterial infections
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
history of recurrent infections ... disease • Infectious ... community-acquired infections ... DDX - Other causes ... infections (Epstein-Barr
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Weight loss - DDX ... : - Infection ... to the knee Infectious ... Disease Post-Infectious ... Hematologic - Leukemia
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Infections 2. ... symptoms - Headache, fever ... infiltration (lymphocytes ... neutrophils and eosinophils