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oncology leukemia chronic agglutinin classification cold common cvid dress eosinophilia eosinophils gap globulin hemeonc hemolytic hes hodgkins hypereosinophilia icl idiopathic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... • Lymphocytes ... #Chronic #Lymphocytic ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... rnature-appearing lymphocytes ... 500/uL clonal B lymphocytes ... #Chronic #Lymphocytic ... Leukemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... (Chronic Lymphocytic ... Leukemia): • Lymphocytes ... and/or Small Lymphocytic ... #Leukemia #Hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
underlying primary or secondary ... mL or 20% total lymphocyte ... chemotherapy) • Genetic syndromes ... #hematology #Differential ... #Causes #lymphocytopenia
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... Granulomatous lymphocytic ... DDX - Other causes ... #immunology #hematology ... #diagnosis #management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
and Management ... blood eosinophilia Secondary ... Causes: - Allergic ... Myeloproliferative HES - Lymphocytic ... #hematology #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Cold Agglutinin Syndrome ... hemolysis • C3↓ C4 ... younger pts) Differential ... #hematology #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Atypical Lymphocytes ... Resolution > 15 days Differentials ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... • Secondary form ... /aggregate) of CD4 ... UIP, NSIP): • Lymphocytic ... Diagnosis #Management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... #diagnosis #causes ... #hematology
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