11 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... Intravascular Hemolysis ... e.g. lupus, CLL, lymphoma ... #differential # ... diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... of Chronic Disease ... • Bleeding • Hemolysis ... of Chronic Disease ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
kidney disease, ... Retroperitoneal, Uterine • Hemolysis ... hemolytic anemia ... Production #Index #hematology ... #anemia #differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Microangiopathic Hemolytic ... hemolytic anemia ... hemolytic anemia ... #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... to large cell lymphoma ... #oncology #hematology ... #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... #hemolytic #anemia ... #hematology #diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology ... #nonpalpable #dermatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... nodosum • Immune hemolytic ... number of sites of disease ... #hematology #oncology ... #management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Vascular Causes ... Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... #hepatology