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differential oncology leukemia management classification cll lymphocytic thrombocytosis anemia causes common cvid eosinophil eosinophilia gap globulin hemeonc hodgkins hypogammaglobulinemia immunodeficiency
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron ... kidney disease ... Probable bone marrow disorder ... #hematology #diagnosis ... #differential #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Metastatic cancer, Lymphoma ... • Infections: Chronic ... #Algorithm #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Diagnosis Algorithm ... Responsive to Treatment ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... cells can indicate disease ... #diagnosis #workup ... #oncology #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... to large cell lymphoma ... chemotherapy for low-risk disease ... #oncology #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... glucocorticoid treatment ... symptoms (eg, skin ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... lymphoma (SLL) ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Workup: • Full ... number of sites of disease ... Treatment • Early ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... hepatitis • Lymphoma ... Granulomatous lymphocytic ... • Nodules • Lymphoid ... hypogammaglobulinemia #immunology #hematology
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