11 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
• Chronic Lymphocytic ... Leukemia (CBC with Lymphocytes ... - Monoclonal Lymphocytes ... on Biopsy ... Algorithm #Causes #Hematology
IgG4-associated conditions

Diagnosis of IgG4 disease is depending on BIOPSY. While IgG4 levels can be informative (and
is depending on BIOPSY ... really need to see pathology ... plasma cells and lymphocytes ... Even the pathology
Myocarditis
Diagnosis 
• Endomyocardial biopsy (gold standard, rarely performed) 
• Clinical presentation 
• Cardiovascular MRI 
Clinical 
•
Endomyocardial biopsy ... • Antlviral (lymphocytic ... Diagnosis #Management #Cardiology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
nephritis • Skin biopsy ... infiltration by lymphocytes ... azotemia • Skin biopsy ... comparison #table #dermatology
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
Treatment: - Lymphocytic ... diagnosis #management #cardiology ... #summary #biopsy
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
HL (MCHL) - Lymphocyte ... HL (LRHL) - Lymphocyte ... LDHL) - Nodular lymphocyte ... variants) - LN biopsy ... classification #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology: • T lymphocyte ... higher • Liver biopsy ... diagnosis #workup #hepatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... salivary gland) biopsy ... salivary gland) biopsy ... UIP, NSIP): • Lymphocytic ... Nephrogenic DI Hematologic
Acute Rheumatic Fever with Erythema Marginatum - Painless, nonpruritic, red annular macules appeared on the upper
Skin biopsy revealed ... infiltration of lymphocytes ... Clinical #Derm #Pathology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Full-thickness skin biopsy ... demonstrates lymphocytes ... comparison #table #dermatology