33 results
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... Pathogenesis and Clinical ... Findings B & T lymphocyte ... hyperplasia Note: B & T lymphocytes ... the etiology Signs
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cell neoplasm • Lymphocytes ... Absolute blood lymphocyte ... #CLL #Chronic #Lymphocytic
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... other autoimmune diseases ... / Symptoms: - ... Lymphocyte infiltration ... #Symptoms
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Lyme Disease: Early ... and Late Clinical ... SSX (lymphocytic ... #diagnosis #signs ... #symptoms
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
CLINICAL MANIFESTATIONS ... Primary and secondary ... Autoimmune thyroid disease ... Insufficiency #Signs ... #Symptoms #Adrenal
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... • Lymphocytic infiltration ... xeropthalmia) Mouth: • Lymphocytic ... pathophysiology #signs ... #symptoms #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... purpura: Strong sign ... with GCA or as primary ... Rash, arthritis Primary ... elevated protein, lymphocytic
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Pathophysiology: • T lymphocyte ... failure PBC Signs ... and Symptoms: ... but elevated as disease
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Management Summary Primary ... or metastatic disease ... ketoconazole, etomidate) Symptoms ... , infiltrative diseases ... point inhibitors, lymphocytic
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... salivary ducts Clinical ... UIP, NSIP): • Lymphocytic ... ) • Cutaneous vasculitis ... phenomenon (16%) MSK