12 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Coagulation disorders CAUSES ... Quantity: • Primary Causes ... • Secondary Causes ... CAUSES OF PALPABLE
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... • Drug Associated ... • Cogan Syndrome ... LFT • ESR • ANA ... #classification
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... Anti-histone (in drug-induced ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: •
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... considered in all cases ... other causes of ... 19 - PNH - Vasculitis ... pathophysiology #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
atherosclerotic disease, drug ... elevated protein, lymphocytic ... often causes arthritis ... viral infection, drug ... • Cogan syndrome
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Drug Reaction with ... Edema in 70% of cases ... Atypical Lymphocytes ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... - Drug induced ... Leukocytoclastic vasculitis ... #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... ) Classification ... lymphoma #diagnosis #classification ... #hematology #oncology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... telangiectasia) Unknown Drug ... multifactorial mechanisms Hematologic ... neurofibromatosis, vasculitis ... #Differential #Causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
petechiae Causes ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... Aplastic #Anemia #oncology ... #hematology #diagnosis