8 results
Inherited Colorectal Cancer (CRS) Syndromes
Adenomatous Polyposis Syndromes:
 • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Adenomatous Polyposis ... : • "CRC + Endometrial ... Cronkhite-Canada (CC ... #diagnosis #management ... #gastroenterology
Hamartomatous Polyposis Syndromes - Peutz-Jeghers Syndrome (PJS), Juvenile Polyposis Syndrome (JPS), Cowden Syndrome (CS), Cronkhite-Canada (CC),
Hamartomatous Polyposis ... Juvenile Polyposis ... polyps Juvenile Polyposis ... #Syndromes #diagnosis ... #management #gastroenterology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation ... Syndrome in APML ... ATRA treatment Pathophysiology ... initiation • Differential ... #diagnosis #management
Adenomatous Polyposis Syndromes:  Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH associated polyposis (MAP)
✓ Genetic
Syndromes: Familial ... → Turcot Syndrome ... → Gardner syndrome ... #Syndromes #diagnosis ... #management #gastroenterology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
impaired B-cell differentiation ... Granulomatous lymphocytic ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Atypical Lymphocytes ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Lymphocytopenia DIAGNOSTIC ... mL or 20% total lymphocyte ... chemotherapy) • Genetic syndromes ... Lymphopenia #ICL #diagnosis ... #hematology #Differential
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... and Management ... Myeloproliferative HES - Lymphocytic ... #hematology #differential