13 results
algorithm causes management chronic cll generalized lymphocytic pruritus systemic thrombocytosis bandemia cancer cbc classification differentiation gap globulin hemeonc hodgkins lymphoma
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... bone marrow and secondary ... #Hematology #Oncology ... #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... initiation • Differential ... #APML #diagnosis ... #management #hematology ... #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Hyperthyroidism CBC ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #Pruritus #secondary ... #generalized #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Tissue damage • Leukemia ... • Autoimmune diseases ... #differential # ... #WBC #CBC #hematology ... #pathophysiology
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