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algorithm management chronic classification cll common cvid gap globulin hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology lad lymphadenopathy lymphoma lymphomas lymphoproliferative mds
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Leukemia (CBC with ... Lymphocytes) ... - Monoclonal Lymphocytes ... #Causes #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... rnature-appearing lymphocytes ... 500/uL clonal B lymphocytes ... #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
): • Lymphocytes ... CLL (Chronic Lymphocytic ... Leukemia): • Lymphocytes ... and/or Small Lymphocytic ... #Hematology #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
prognosis • Nodular Lymphocyte ... cells absent, lymphocyte ... Mixed Cellularity, Lymphocyte ... Rich, Lymphocyte ... #Hematology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... Granulomatous lymphocytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... HL (MCHL) - Lymphocyte ... HL (LRHL) - Lymphocyte ... LDHL) - Nodular lymphocyte ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... Connective tissue disorders ... gastric tumors • Hematology ... #diagnosis #hematology
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