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diagnosis hematology differential anemia management vasculitis algorithm oncology types approach cold common comparison cryoglobulinemia cryoglobulins cvid hemolytic hodgkins hypogammaglobulinemia immunodeficiency
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Renal Disease, Liver ... #Anemia #MCV #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
the population Disease ... decades of life Causes ... fever, fatigue, Nausea ... infiltration (lymphocytes ... Urticaria #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... -> AML: Blast crises ... CLL (Chronic Lymphocytic ... #Leukemia #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Liver disease ... Intravascular Causes ... #classification ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Anemia of Chronic Disease ... Non-lmmune #Anemia #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... Granulomatous disease ... Granulomatous lymphocytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... HL (MCHL) - Lymphocyte ... number of sites of disease ... lymphoma #diagnosis #classification ... #hematology #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... UIP, NSIP): • Lymphocytic ... Sjogrens #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... (Granulomatous disease ... atherosclerotic disease ... differential #diagnosis #rheumatology ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... diagnosis #types #classification ... #rheumatology #
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