27 results
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Cold Urticaria Prevalence ... decades of life Causes ... fever, fatigue, Nausea ... infiltration (lymphocytes ... Urticaria #diagnosis #rheumatology
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
and/or toes) to cold ... Raynauds #Syndrome #disease ... clinical #video #physicalexam ... fingers #hands #rheumatology
Raynaud's Syndrome - Washing off under hot water wath.

Raynaud phenomenon is an exaggerated vasoconstrictive response of
and/or toes) to cold ... Raynauds #Syndrome #disease ... clinical #video #physicalexam ... fingers #hands #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... Extravascular #Causes ... differential #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Liver disease ... • AIHA: warm, cold ... Intravascular Causes ... classification #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... -> AML: Blast crises ... CLL (Chronic Lymphocytic ... #Leukemia #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
practices that could ... cause nutrient ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... #Workup #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... may include: • Cold ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Claudication) - Cold ... Peripheral Vascular Disease ... Diagnosis #Algorithm #Orthopedics ... #Causes
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... Pain #SickleCell #Disease ... #hematology