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diagnosis management hematology syndrome oncology dermatology differential leukemia lupus sle vasculitis chronic clinical cll comparison erythematosus hemophagocytic hlh lymphohistiocytosis neurology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
transformation) Treatment ... chemotherapy for low-risk disease ... Indications for Treatment ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
the population Disease ... decades of life Causes ... fever, fatigue, Nausea ... infiltration (lymphocytes ... Urticaria #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... -> AML: Blast crises ... CLL (Chronic Lymphocytic ... #Leukemia #Hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... by case) • Surgery ... #Syndrome #Treatment ... #pharmacology #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis, causes ... neuropathy Treatment ... with refractory disease ... Cryoglobulinemia #Vasculitis #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... Granulomatous disease ... Granulomatous lymphocytic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... normal in mild cases ... by a hemophilia treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
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