17 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
- Differential ... of hair, eyes, skin ... Tanning • Adverse cutaneous ... • Addison's disease ... #dermatology #Differential
Skin Hyperpigmentation - Differential Diagnosis Algorithm
Diffuse:
 • Tanning
 • Adverse cutaneous drug eruption
 • Addison's disease
Skin Hyperpigmentation ... - Differential ... Tanning • Adverse cutaneous ... • Addison's disease ... #dermatology #Differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... : GI, neuro, cutaneous ... involvement Differential ... • Other hematologic ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... Hepatomegaly • Skin ... cells can indicate disease ... workup #oncology #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... Vasculitis #dermpath #dermatology ... lesions #diagnosis #clinical ... manifestations #pathology ... #lesions #differential
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... • Non-Hodgkin lymphoma ... • Angiocentric lymphoma ... Polyangiitis #GPA #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... violaceous, nontender cutaneous ... lymphoma (SLL) ... CLL -> Invade Skin ... #Leukemia #Hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology: • T lymphocyte ... Examination: • Skin ... hyperpigmentation ... bile ducts Differential ... Endocrinopathy, Lymphoma
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... hypertrichosis, hyperpigmentation ... Paraproteinemias #Hematology ... #Monoclonal #Differential