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nephrology differential causes algorithm management nephrotic renal treatment workup acute aki comparison hematuria hypokalemia nephritic proteinuria rhabdomyolysis blood diseases hyponatremia
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... disease • Granular casts ... #nephrology #casts
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology ... #Diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... pain hematuria syndrome ... hematuria: - RBC casts ... → Diagnostic of ... #nephrology #renal
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology ... #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... • Drugs Glomerular ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic sydnrome ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... Guillain-Barré syndrome ... Hyperreflexia: • Hypocalcemia ... #differential #diagnosis ... #table #neurology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... • Evidence of glomerular ... proteinuria, RBC casts ... → Refer to Nephrology ... if cause not identified
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts ... #Differential #Diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Diagnosis #Nephrology
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